Effects of inflammation in dental pulp cell differentiation and reparative response

The responsiveness of the dentin-pulp complex is possible due to stimulation dental pulp cells, which begin synthesize and secrete dentin matrix. inflammatory process generated by harmful stimuli should be understood as a natural event immune response, resulting in recruitment hematopoietic cross endothelial barrier reach site affected injury order eliminate damage provide an appropriate environment for restoration homeostasis. repair occurs presence adequate blood supply, absence infection, with participation pro-inflammatory cytokines, growth factors, extracellular matrix components, other biologically active molecules. Prostaglandins leukotrienes are bioactive molecules derived from metabolism arachidonic acid, result variable range cellular stimuli. aim this review describe formation biomineralization how events can modify emphasis on lipid mediators prostaglandins acid metabolism.